Principal Investigator-Protein Biochemistry
ID 2013-1018
No of Openings 1
Job Location IN-New Delhi
Category Research and Development
More information about this job:
Overview:The International AIDS Vaccine Initiative (IAVI) is a nonprofit scientific and charitable organization founded in 1996 whose mission is to ensure the development of safe, effective, accessible, preventive HIV vaccines for use throughout the world. IAVI's work focuses on four areas: accelerating scientific progress; mobilizing public support through issue advocacy and education; encouraging industrial involvement in AIDS vaccine development; and working to assure global access to a vaccine. IAVI is a dynamic and mission-driven organization, and the work environment is fast-paced and intellectually stimulating, relying on the good cheer and high level of cooperation of its committed members.
Overview:The International AIDS Vaccine Initiative (IAVI) is a nonprofit scientific and charitable organization founded in 1996 whose mission is to ensure the development of safe, effective, accessible, preventive HIV vaccines for use throughout the world. IAVI's work focuses on four areas: accelerating scientific progress; mobilizing public support through issue advocacy and education; encouraging industrial involvement in AIDS vaccine development; and working to assure global access to a vaccine. IAVI is a dynamic and mission-driven organization, and the work environment is fast-paced and intellectually stimulating, relying on the good cheer and high level of cooperation of its committed members.
Responsibilities:Principal Investigator-THSTI-IAVI HIV Vaccine Design Program (HVTR laboratory)
Translational Health and Science Technology Institute (THSTI) and International AIDS Vaccine Initiative (IAVI), USA is seeking Principal Investigator for its THSTI-IAVI HIV Vaccine Design Program (HVTR laboratory).
HVTR aims to accelerate and advance HIV vaccine research and development and shall be an integral part of the THSTI cluster of research centers and will be closely linked to global network of R&D facilities, including IAVIs Neutralizing Antibody Consortium (NAC) and IAVI Design and Development lab, situated in Brooklyn, New York. HVTR would be an innovative discovery program and will be directed at designing, testing and implementing high-throughput (HT) strategies for HIV-1 envelope-based immunogen screening and prioritization to help discover and advance novel HIV vaccine candidates. The program is targeted to expand the number of vaccine candidates for testing, and enhance the speed with which they can be assayed. The unique industrial-type high-throughput vaccine design, screening and selection processes proposed will be largely facilitated by interdisciplinary interaction and thus driven by principles of international collaboration, high-quality science and vaccine-oriented applied research.
Key Responsibilities:The Principal Investigator (PI) will formulate, lead, and guide all scientific aspects of the Program related to his/her area of research under the broad direction of the Program Director. The Principal Investigator (PI) is charged to conduct research that generates independent, high quality, and reproducible results. The Principal Investigator is responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships. Additionally, the Principal Investigator is responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project and for coordination with other departments within the program to assure research is conducted in accordance with established regulations and THSTI-IAVI policies and procedures. The PI also has primary responsibility for achieving the technical success of the program, while also complying with the financial and administrative policies and regulation for the THSTI-IAVI program. Specific responsibilities include:
• Administers and oversees research and all related activities related to his/her group.
• Execute the project as outlined in the work plan, using sound management techniques
• Develop and manage the project’s budget & financial plan or make changes to the plan following a prescribed set of policies and procedures.
• Review, preparation and monitor the necessary scientific protocol to ensure compliance with policies and procedures.
• Oversee the conduct of research and research team to help ensure ethical conduct in all aspects of the research process including but not limited to conflicts of interest, data acquisition, management, sharing and ownership, publication practices, responsible authorship, and collaborative research and reporting.
• Obtain, maintain, and safeguard equipment used to conduct research
• Report on project progress as outlined in the project plan and maintain accurate records of project related activities and expenses.
Translational Health and Science Technology Institute (THSTI) and International AIDS Vaccine Initiative (IAVI), USA is seeking Principal Investigator for its THSTI-IAVI HIV Vaccine Design Program (HVTR laboratory).
HVTR aims to accelerate and advance HIV vaccine research and development and shall be an integral part of the THSTI cluster of research centers and will be closely linked to global network of R&D facilities, including IAVIs Neutralizing Antibody Consortium (NAC) and IAVI Design and Development lab, situated in Brooklyn, New York. HVTR would be an innovative discovery program and will be directed at designing, testing and implementing high-throughput (HT) strategies for HIV-1 envelope-based immunogen screening and prioritization to help discover and advance novel HIV vaccine candidates. The program is targeted to expand the number of vaccine candidates for testing, and enhance the speed with which they can be assayed. The unique industrial-type high-throughput vaccine design, screening and selection processes proposed will be largely facilitated by interdisciplinary interaction and thus driven by principles of international collaboration, high-quality science and vaccine-oriented applied research.
Key Responsibilities:The Principal Investigator (PI) will formulate, lead, and guide all scientific aspects of the Program related to his/her area of research under the broad direction of the Program Director. The Principal Investigator (PI) is charged to conduct research that generates independent, high quality, and reproducible results. The Principal Investigator is responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships. Additionally, the Principal Investigator is responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project and for coordination with other departments within the program to assure research is conducted in accordance with established regulations and THSTI-IAVI policies and procedures. The PI also has primary responsibility for achieving the technical success of the program, while also complying with the financial and administrative policies and regulation for the THSTI-IAVI program. Specific responsibilities include:
• Administers and oversees research and all related activities related to his/her group.
• Execute the project as outlined in the work plan, using sound management techniques
• Develop and manage the project’s budget & financial plan or make changes to the plan following a prescribed set of policies and procedures.
• Review, preparation and monitor the necessary scientific protocol to ensure compliance with policies and procedures.
• Oversee the conduct of research and research team to help ensure ethical conduct in all aspects of the research process including but not limited to conflicts of interest, data acquisition, management, sharing and ownership, publication practices, responsible authorship, and collaborative research and reporting.
• Obtain, maintain, and safeguard equipment used to conduct research
• Report on project progress as outlined in the project plan and maintain accurate records of project related activities and expenses.
Qualifications:
Key Capabilities and Experience:• A PhD or other equivalent degree in Chemistry, Biochemistry or any other discipline of Life Sciences with at least 8 years of work experience after PhD in the Candidates with work experience in HIV research with understanding of either one or more of the following areas would be preferred:
o B-cell biology or
o molecular biology and bioinformatics or
o protein purification, physicochemical characterization and protein structure
o The candidate should have expertise in either of the one field given below:
o In-depth experience in molecular biology, protein expression, protein purification, functional and physico-chemical characterization. Candidates with understanding of protein design and protein structure-function relationship would be preferred
or
• In-depth experience in immunology especially on B-cell biology. Candidates with understanding of antibody to control HIV-1 infection will be preferred
• Significant record of professional accomplishment including publications, patents and invited speaking engagements; experience in developing country realities, and expertise in areas relevant to the project
• Believes in the potential of collaborative approaches to problem solving; able to contribute to and follow the project plan with minimal guidance from the Program Director.
• Experienced in leading and mentoring a group of scientists.
• Ability to manage short-term and long-term lab resource needs and facility budgets to achieve the set objectives.
• Effective scientific communicator as evidenced by publications and presentations at scientific meetings.
• An understanding of priority-setting, resource management and the bridge-building required to foster scientific cooperation.
• Encourages open communication and participation with an emphasis on transparency and the sharing of information.
• Able to handle challenging situations, including daunting tasks and complex interpersonal issues, with a calm, assured, unflagging approach that keeps all “eyes on the prize.”
• A champion of innovation who responds to complex problems and challenges by applying new perspectives and exploring a variety of relevant possible solutions.
• A team player and team-builder who is willing to work with and patiently align diverse stakeholders who maintain their individual autonomy and decision-making.
Key Capabilities and Experience:• A PhD or other equivalent degree in Chemistry, Biochemistry or any other discipline of Life Sciences with at least 8 years of work experience after PhD in the Candidates with work experience in HIV research with understanding of either one or more of the following areas would be preferred:
o B-cell biology or
o molecular biology and bioinformatics or
o protein purification, physicochemical characterization and protein structure
o The candidate should have expertise in either of the one field given below:
o In-depth experience in molecular biology, protein expression, protein purification, functional and physico-chemical characterization. Candidates with understanding of protein design and protein structure-function relationship would be preferred
or
• In-depth experience in immunology especially on B-cell biology. Candidates with understanding of antibody to control HIV-1 infection will be preferred
• Significant record of professional accomplishment including publications, patents and invited speaking engagements; experience in developing country realities, and expertise in areas relevant to the project
• Believes in the potential of collaborative approaches to problem solving; able to contribute to and follow the project plan with minimal guidance from the Program Director.
• Experienced in leading and mentoring a group of scientists.
• Ability to manage short-term and long-term lab resource needs and facility budgets to achieve the set objectives.
• Effective scientific communicator as evidenced by publications and presentations at scientific meetings.
• An understanding of priority-setting, resource management and the bridge-building required to foster scientific cooperation.
• Encourages open communication and participation with an emphasis on transparency and the sharing of information.
• Able to handle challenging situations, including daunting tasks and complex interpersonal issues, with a calm, assured, unflagging approach that keeps all “eyes on the prize.”
• A champion of innovation who responds to complex problems and challenges by applying new perspectives and exploring a variety of relevant possible solutions.
• A team player and team-builder who is willing to work with and patiently align diverse stakeholders who maintain their individual autonomy and decision-making.
The position is currently based in Gurgaon, National Capital Region of Delhi, India and will be contractual basis and the compensation shall be industry competitive and commensurate with experience. The position will report to the Program Director- THSTI IAVI HIV Vaccine Design Program. The program offers an enabling environment with tremendous opportunities for growth. Interested candidates may please send in their applications with a cover note, current curriculum vitae and bibliography, together with a brief description of past and present scholarly interests and accomplishments and names of three references.
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